Drosophila melanogaster midgut shown in bright colors

Art of Science: Beauty in Fruit Flies

Science and Art Take Guts

Using fruit flies as a research model, Tanja Godenschwege, Ph.D., is unraveling the mysterious connection of how a person's gut impacts their mood, their brain, their behavior and even the onset of neurodegenerative diseases like Alzheimer's.

“Most people think of the gut as ugly because they associate it with its final product,” said Godenschwege, professor, Charles E. Schmidt College of Science. “But when you look closely, it's astonishingly beautiful.”

Godenschwege and several of her students recently earned accolades for images of their research submitted to the annual Art of Science, an initiative that highlights photographs and videography of research happening across the colleges at Florida Atlantic University.

“Our images show the elegance that can be found in science while also reminding us how important the proper communication between gut and brain is to human health,” Godenschwege said. “Miscommunication leads to obesity, diabetes, mood disorders and neurodegeneration.”

Godenschwege's winning image, titled Owls Having Guts, earned an honorable mention. Captured with a microscope, the image reveals the intricate structure of the fruit fly digestive system. Her students' entries reflected their emerging scientific skills.

Here is a look at some of her students' winning submissions:

double-labeled image of a fruit fly gut in bright colors
Face of Digestion, Research Excellence recognition, by Emily Arbesfeld, shows a double-labeled image of a fruit fly gut – specifically the endogenous protein which has been linked to metabolic disorders such as diabetes and obesity. Learn more about Face of Digestion.
triple-labeled fruit fly stomach in bright colors
Gut Gathering, honorable mention, Fernanda Salomao Del Bianco, shows a triple-labeled fruit fly stomach. The research is about understanding the role of transmembrane proteins in the communication between the gut and brain to regulated feeding behavior and neuronal health. Learn more about Gut Gathering.
insulin producing cells of the common fruit fly in bright colors
Fruit Fly Desire, honorable mention, Katherine Sankey, depicts the insulin producing cells and diuretic hormone 44 of the common fruit fly, stained and arranged to resemble the fly's head. The cells and hormones used play a crucial role in detecting dietary amino acids which promote consumption behaviors and contribute to maintaining metabolic homeostasis. Learn more about Fruit Fly Desire.
mammalian         transmembrane protein in bright colors
Spaced Out Eggs, honorable mention, Tiarra Steadman, displays fruit fly oocytes at different developmental stages nested next to the fruit fly gut. The mammalian transmembrane protein pictured is a multifunctional protein with roles in maturation, energy homeostasis, appetite regulation, immune responses and pigmentation. Learn more about Spaced Out Eggs.

For Godenschwege, her students' success is more meaningful than her own, she said.

“My students spend many hours learning and then executing tedious dissections of these tiny fruit flies to obtain these beautiful images,” she said. “Seeing them recognized for that hard work is incredibly rewarding. I'm proud of my honorable mention but watching my students succeed is even better.”

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