Dr. Wen Shen, Ph.D

Wen Shen, Ph.D., is an Associate Professor of Biomedical Science. Dr. Shen’s research interests include neural signal processing, ion channel and receptor physiology, and neural system remodeling as well. Research in her laboratory is aimed at understanding cellular and molecular mechanisms of synaptic connection, network modulation, and neuroplasticity in the central brain and sensory system.

• 1999: Ph.D., Physiology and Biophysics, State University of New York at Buffalo

• 2007-Present: Associate Professor, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida
• 2010-Present: Adjunct Associate Professor, Center for Complex System and Brain Science, College of Science, Florida Atlantic University, Boca Raton, FL
• 2003-2007: Assistant Professor, College of Biomedical Science, Florida Atlantic University, Boca Raton, Florida
• 2004-2007: Adjunct Associate Professor, Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, Florida
• 1999-2003: Research Assistant Professor, State University of New York at Buffalo
• 1993-1998: Graduate Research Assistant, Department of Physiology and Biophysics, State University of New York at Buffalo
• 1988-1993: Research Specialist, Shanghai Institute of Physiology, Chinese Academy of Science, Shanghai, P.R. China
• 1983-1988: Engineer, Research Institute of Environmental Control and Protection, Shanghai Municipal Bureau of Chemical Industry, Shanghai, P.R. China

• Yang, J., Nan, C.-L., Ripps, H. & Shen, W. (2015). Destructive Changes in the Neuronal Structure of the FVB/N Mouse Retina. PLoS One, 10(6): e0129719.
• Z Jiang, JN Yang, LA Purpura, YF liu, H Ripps, W Shen (2014) Glycinergic feedback enhances synaptic gain in the distal retina. J Physiol. (London), 592: 1479-1492. PMCID: PMC3979606
• W Shen, LA Purpura, Baoqin Li, CL Nan, IJ Chang and H Ripps (2013) Regulation of Synaptic Transmission at the Photoreceptor Terminal: A Novel Role for the Cation-Chloride Cotransporter NKCC1. J Physiol. (London), 591:133-147. PMCID: PMC3630777
• S Bulley, YF Liu, H Ripps, and W Shen (2013) Taurine Activates Delayed Rectifier KV Channels via a Metabotropic Pathway in Retinal Neurons". J Physiol. 591:123-132.
• H Ripps and W Shen (2012) Taurine: An exceedingly ‘Essential’ amino acid. Molecular Vision. 18:2673-2686.
• M JM Rowan, H Ripps and W. Shen. Fast glutamate uptake via EAAT2 shapes the cone-mediated light offset response in bipolar cells. J Physiol. 588: 3943-3956. (2010).
  
  

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Research Interests

• Electrophysiology of channels and receptors
• Transporters in neurodevelopment and adult system
• Signal transduction in retinal circuit