Kathleen M. Guthrie, Ph.D.

Kathleen M. Guthrie

Assistant Director and Director of Graduate Education, Neuroscience Graduate Program, FAU Brain Institute | Professor, Biomedical Science

777 Glades Road

Boca Raton, FL 33431

BC 71, Room 208

p: 561-297-0457


Department: Biomedical Science


Kathleen Guthrie, Ph.D., serves as an Professor of Biomedical Science at the Charles E. Schmidt College of Medicine. Dr. Guthrie received her Ph.D. training in Neuroscience at the University of California, Irvine. Dr. Guthrie's group in the Guthrie Research Lab investigate development and survival of new neurons in the adult brain in mouse models of neurological disorders, including Huntington’s disease, epilepsy and autism spectrum disorders. Dr. Guthrie serves as Assistant Director of Education for the FAU Brain Institute, and is on the Editorial Board of the Journal Scientific Reports.


  • BS in Biology, Cum Laude, 1980, Fort Lewis College, Durango Colorado
  • BS in Chemistry, 1982, Fort Lewis College, Durango Colorado
  • PhD in Neuroscience and Behavior, 1989, University of California Irvine

Work History

  • 2017-present, Affiliate Faculty, Division of Neurology, Dept. of Integrated Medicine, Charles E. Schmidt College of Medicine, Florida Atlantic University
  • 2001-present, Associate Professor, Dept. of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University
  • 1990-2001: University of California, Irvine/Research Assistant Professor

Scholarly Activity

Research Interests

  • Adult brain neurogenesis and stem cells
  • Neural development, plasticity and trophic signaling
  • Olfactory-limbic System
  • Genetic mouse models of neurological disorders

Selected Peer-Reviewed Publications

  • Smail S, Bahga D, McDole B, Guthrie, K. (2016) Increased olfactory bulb BDNF expression does not rescue deficits in olfactory neurogenesis in the Huntington's disease R6/2 mouse. Chem. Senses, 41:221-232.
  • Isgor C, Pare C, McDole B, Coombs P, Guthrie, K. (2015) Expansion of the dentate mossy fiber-CA3 projection in the brain-derived neurotrophic factor enriched hippocampus. Neuroscience, 288:10-23. PMC:4324623. NIHMS652724.
  • Liu H., Lu M, Guthrie K. (2013) Anterograde trafficking of neurotrophin-3 in the adult olfactory system in vivo. Exper. Neurol. 241:125-137. PMC:3570701
  • McCollum MH, Leon RT, Rush DB, Guthrie KM, Wei J. (2013) Striatal oligodendrogliogenesis and neuroblast recruitment are increased in the R6/2 mouse model of Huntington's disease. Brain Research, 1518:91-103. PMC3684253
  • Liu H and Guthrie K. (2011) Neuronal replacement in the injured olfactory bulb. Exper. Neurol. 228:270-282. PMCID: PMC3063445.
  • Sultan-Styne K, Toledo R, Walker C, Kallkopf A, Ribak C, Guthrie K. (2009) Long-term survival of olfactory sensory neurons after target depletion. J Comp. Neurol. 515:696-710. PMCID: PMC2728470.

View Pubmed Feed

Additional Information
The Charles E. Schmidt College of Medicine offers students a variety of educational programs and degrees.
Charles E. Schmidt College of Medicine
Florida Atlantic University
777 Glades Road, BC-71
Boca Raton, FL 33431