Jacqueline Freire Machi, Ph.D.

Jacqueline Freire Machi

Research Assistant Professor

777 Glades Road

Boca Raton, FL 33431

BC 71, Room 220

p: 561-297-4434

jfreiremachi@health.fau.edu

Department: Biomedical Science

Biography

Jacqueline Freire Machi received her Ph.D. in cardiovascular physiology from University of Sao Paulo, Brazil. Her doctoral work focused on understanding the mechanisms by which metabolic disease triggers cardiovascular dysfunction for the development of therapeutic strategies including exercise. Throughout her career, with approximately 15 years of research experience she developed a solid background in metabolism, autonomics, exercise training and cardiovascular physiology in the context of metabolic syndrome, aging and toxic chemical exposure. During her pre- and postdoctoral studies, she received training on the use of echocardiography for assessment of cardiac function, analysis of autonomic activity of blood pressure and metabolism.

In 2021, Dr. Machi joined Florida Atlantic University Charles E. Schmidt College of Medicine as an Assistant Professor in the department of Biomedical. Her short-term research goal is to understand the role of endothelial c-Myc preventing obesity and cardiovascular dysfunction. Her long-term research goal, is to develop an independent research program in obesity-associated co-morbidities to better understand the mechanisms associated with these conditions for development of preventative and therapeutic strategies that can be translated to clinic.

Education

  • 2007: B.S., Physical Education, São Judas Tadeu University, São Paulo, Brazil.
  • 2010: M.S., Exercise Physiology, São Judas Tadeu University, São Paulo, Brazil.
  • 2015: Ph.D., Physiology/Cardiovascular, University of Sao Paulo, São Paulo, Brazil.
  • 2018: Post-Doctoral., Cardiotoxicity, Nova Southeastern University, Davie, Florida.
  • 2021: Post-Doctoral., Vascular Biology, University of Miami, Miami, Florida.

Work History

  • 2021-Present: Research Assistant Professor, Department of Biomedical Science, Florida Atlantic University, Boca Raton, FL.
  • 2018-2021: Postdoctoral Associate, Department of Molecular and Cellular Pharmacology, University of Miami, Florida, FL.
  • 2017-2018: Postdoctoral Research Associate, Department of Neuro Immune Medicine, Nova Southeastern University, Davie, FL.
  • 2015-2017: Research Associate, Department of Neuro Immune Medicine, Nova Southeastern University, Davie, FL.
  • 2014-2018: Research Scientist, Miami VA Health Care System, Miami, FL, USA.

Peer-Reviewed Publications

Scholarly Activity

Research Support

President's Faculty Research and Development Grant. Role: PI from Nova Southeastern University (2017-2018). Dietary fructose as a risk factor for Gulf War Illness: Exercise Challenge.

President's Faculty Research and Development Grant. Mariana Morris. Role: Co-investigator from Nova Southeastern University. (2018-2019). A Neurotoxin Model: Effects on cardiovascular, autonomic and oxidative stress profile.

Honors

Postdoctoral Minority Fellowship Award. Jacqueline Machi, PhD, Angiocrine Signals in Metabolic Dysfunction. American Diabetes Association. March 2020 (This award was canceled due to the COVID-19 financial crisis).

Platform presentation at the American Heart Association Scientific Sessions 2019, Session Title: Novel insights into coronary arterial disease and aging. Philadelphia, PA. Loss of Endothelial c-Myc triggers visceral fat accumulation in aging mice associated with serum increase in cholesterol and leptin

Travel Award - Arteriosclerosis, thrombosis, and Vascular Biology (ATVB). Grant for Early Career Investigators. Title: Loss of Endothelial c-Myc triggers visceral fat accumulation in aging mice associated with serum increase in cholesterol and leptin. American Heart association, Scientific Sessions in Philadelphia, PA 2019.

Honorable Mention, Young Investigator Basic Science Presentation. Exercise Training Improves Cardiac Function in Mice Exposed to a Model of Gulf War Illness: Combined use of Corticosterone and Diisopropyl fluorophosphate (DFP). Miami VA Research Day 2016.

Educational award, European Society of Cardiology (ESC) Grants. This grant aims to encourage and support the development of the professional careers towards the fight against cardiovascular disease. Annual meeting ESC: Italy Rome 2016.

Master Fellowship – State of Sao Paulo Research Foundation (FAPESP) – (2009-2012). Brazilian National Research Council

Pre-doctoral Fellowship – Brazilian National Research Council (CAPES) – (2012-2015). Brazilian National Research Council.

International Scholarship – Brazilian National Research Council (CNPQ) – (2014). Research exchange program between University of Sao Paulo Brazil and Nova Southeastern University, Florida.

Second place award for best undergraduate project, Physical Education bachelor's degree. Comparison of cardiovascular responses to exercise training between males and females, São Judas Tadeu University.

Additional Information
The Charles E. Schmidt College of Medicine offers students a variety of educational programs and degrees.
Address
Charles E. Schmidt College of Medicine
Florida Atlantic University
777 Glades Road, BC-71
Boca Raton, FL 33431
(561) 297-4828