12 Signs of Bad Gut Health

Thursday, Feb 05, 2026
Woman holding her stomach in distress

When something about your body doesn’t feel right, digestion is often part of the story.

Many people begin to question their gut health after months (or even years) of persistent symptoms that never fully resolve. These concerns are usually disruptive, not minor. They can include ongoing digestive distress, chronic fatigue, inflammation that interferes with daily life, changes in mood or cognition, and other health issues that continue to progress despite repeated attempts at treatment. Typically, the symptoms don’t point neatly to a single diagnosis, making them difficult to explain and frustrating to live with.

If you’ve been experiencing ongoing symptoms that haven’t improved or haven’t been fully explained, gut health may be an important part of the picture. The 12 signs and symptoms below are intended to help you better understand whether your gut may be contributing to persistent health challenges and whether a more comprehensive evaluation may be appropriate.

Why Gut Health Is So Important

Gut health plays a critical role in immune regulation, inflammation control, hormone signaling, and communication with the brain and nervous system. When the gut isn’t functioning properly, the consequences can be widespread and significant, affecting energy, resilience, recovery, and overall quality of life.

A large portion of the immune system is housed in the gut. When the gut lining is compromised or the microbial balance is disrupted, the immune system can become chronically activated. Over time, this can contribute to widespread inflammation and increase vulnerability to a range of health conditions, from autoimmune issues to metabolic dysfunction. Conventional tests may appear normal, but the body is signaling that something is out of balance.

The intestines are also a key player in brain health. Through what is often called the gut–brain connection, signals travel continuously between the digestive system and the nervous system. When gut function is impaired, those signals can be altered, affecting mood, cognitive clarity, stress resilience, and sleep. Symptoms like brain fog, anxiety, or low energy can sometimes trace back to digestive imbalance—even when digestion itself doesn’t seem like the primary issue.

At the Marcus Institute of Integrative Health at Florida Atlantic University, we recognize that gut health is the foundation of well-being, rather than a single problem to treat. Understanding and supporting your gut health is often a critical step in addressing complex, persistent overall health concerns and restoring overall balance.

12 Signs and Symptoms of Poor Gut Health

1. Upset Stomach and Other Abdominal Pain

Ongoing abdominal discomfort is the most direct signal that the gut might not be functioning properly. This can include cramping, burning, pressure, or generalized pain that comes and goes—or persists despite treatment.

When these symptoms are recurrent or difficult to pinpoint, they may reflect inflammation, altered gut motility, or disruptions in how the digestive system processes food and signals distress.

2. Gas and Bloating

Excessive gas and bloating are often dismissed as minor or diet-related, but when they occur frequently, they can indicate imbalances in the gut microbiome or impaired digestion. Bloating that worsens throughout the day or appears unrelated to specific meals may suggest that the gut is struggling to break down food efficiently or maintain a healthy balance of bacteria.

3. Diarrhea, Constipation, and Other Stool Changes

Changes in stool frequency, consistency, or appearance can be important indicators of gut dysfunction. Chronic diarrhea, ongoing constipation, or alternating between the two may indicate underlying inflammation, impaired gut signaling, or an altered microbial balance. The presence of mucus, excessive foul odor, or stools that float may also suggest that digestion or nutrient absorption isn’t working as it should. These patterns often reflect deeper disruptions rather than isolated digestive issues.

4. Food Intolerances

New sensitivity to foods that were once well tolerated can be a sign that the gut lining or the gut's immune response has changed. Food intolerances may present as digestive symptoms, headaches, fatigue, or skin reactions, and often indicate that the gut is reacting abnormally to certain triggers rather than processing them smoothly.

5. Fatigue

Persistent fatigue that doesn’t improve with rest or sleep is commonly linked to an unhealthy gut. When digestion, nutrient absorption, or immune regulation is impaired, the body may struggle to maintain energy levels. Inflammation originating in the gut can also place a chronic strain on the system, contributing to ongoing exhaustion.

6. Trouble Sleeping

Likewise, sleep disturbances are frequently connected to gut imbalance. The gut plays a role in regulating neurotransmitters and hormones involved in sleep cycles. When gut function is disrupted, it can interfere with the body’s ability to fall asleep, stay asleep, or feel restored after rest.

7. Migraines

Migraines and recurrent headaches have been increasingly associated with gut-related inflammation and altered gut–brain communication. For some individuals, digestive imbalance may act as a trigger or contributing factor, especially when migraines occur alongside gastrointestinal symptoms or food sensitivities.

8. Mood Changes or Cognitive Problems

The gut and brain are constantly communicating, and disruptions in gut health can affect mood, focus, and mental clarity. Symptoms such as anxiety, low mood, irritability, or brain fog may reflect altered signaling along this gut–brain connection, especially when emotional stress doesn’t seem to fully explain the changes.

9. Autoimmune Problems

Gut health plays a significant role in immune regulation. When the gut barrier is compromised or immune signaling becomes dysregulated, it may contribute to autoimmune activity. While gut dysfunction is rarely the sole cause, it’s often a meaningful factor in the broader immune picture.

10. Allergies and Skin Irritation

Skin conditions such as rashes, eczema, acne, or unexplained irritation can sometimes trace back to gut imbalance. The gut influences immune responses and inflammatory pathways that affect the skin, making chronic or treatment-resistant skin issues a potential external sign of internal disruption.

11. Unexplained Weight Changes

Unexpected weight gain or weight loss can be associated with changes in gut health that affect metabolism, hormone regulation, and nutrient absorption. When the gut is not functioning optimally, the body may struggle to maintain a stable metabolic balance, even without changes in diet or activity.

12. Intense Cravings

Strong or persistent cravings—particularly for sugar or refined carbohydrates—may be linked to gut microbial imbalances. Certain bacteria can influence appetite signals and cravings, making dietary choices feel harder to control when gut health is compromised.

How Gut Health Affects the Rest of the Body

The gut plays a central role in overall physical and mental health. The gut helps regulate neurotransmitters such as serotonin, which influences mood, sleep, and emotional stability. Imbalances in the gut have been linked to mood disorders, cognitive changes, and difficulty managing stress levels, even when digestive symptoms aren’t the primary concern.

The gut is also closely linked to the immune system, which resides in the digestive tract and relies on healthy microbial signaling to function properly. Disruptions in this process may contribute to chronic inflammation and immune dysregulation, which are associated with autoimmune conditions, inflammatory bowel disease (including Crohn’s disease, irritable bowel syndrome (IBS), and ulcerative colitis), and inflammatory skin conditions such as psoriasis.

Metabolic health is also influenced by gut function. Changes in the gut microbiome can affect nutrient absorption, energy storage, and body weight regulation—factors that may contribute to obesity or unexplained weight changes. Digestion and absorption occur primarily in the small intestine, while waste processing and immune signaling involve the large intestine, so dysfunction at any point in the gut can have system-wide consequences.

The Role of the Gut Microbiome

The gut microbiome is the complex community of bacteria and other microorganisms that live in the digestive tract. These microbes play an active role in digestion, nutrient absorption, immune regulation, inflammation control, metabolism, and communication with the brain and nervous system.

A healthy microbiome is diverse and balanced, helping the body function smoothly across multiple systems. When that balance is disrupted, however, a state often referred to as dysbiosis, the effects can extend far beyond the gut itself. Changes in the microbiome may contribute to chronic inflammation, altered immune responses, increased food sensitivities, and disruptions in gut–brain signaling.

Factors that can influence the gut microbiome include:

  • Diet, including fiber intake and food variety
  • Chronic or acute stress
  • Antibiotic use and other medications
  • Sleep quality and circadian rhythm disruption
  • Illness or infection
  • Environmental exposures and toxins
  • Hormonal changes
  • Physical activity levels

Because the microbiome is constantly adapting, changes in these areas—whether gradual or sudden—can meaningfully affect gut health and overall wellness.

Ways to Improve Your Gut Health

Improving gut health often starts with small, consistent changes that support the balance of gut bacteria and overall digestive health. The foods you eat help shape the balance of beneficial bacteria and good bacteria in the digestive tract. Lifestyle factors also play a significant role. Poor sleep, elevated stress levels, dehydration, and limited physical activity can all negatively affect gut function.

Common ways to support gut health include:

  • Reducing intake of processed foods and added sugars
  • Eating more fiber-rich foods such as vegetables, legumes, and whole grains
  • Including fermented foods like kefir, kimchi, sauerkraut, and kombucha, when tolerated
  • Supporting beneficial microbes with prebiotics and probiotics, when appropriate
  • Drinking plenty of water to support digestion and stool consistency
  • Paying attention to how foods like gluten affect your symptoms
  • Managing stress levels through rest, movement, and recovery
  • Being cautious with supplements and using them intentionally rather than indiscriminately

These strategies can support a healthy gut, but they aren’t one-size-fits-all solutions. Individuals with chronic digestive symptoms, autoimmune conditions, or diagnosed gastrointestinal disorders may need a more personalized approach that considers the unique interactions between diet, lifestyle, and the digestive system.

Prioritize your well-being today. Schedule a consultation with the Marcus Institute of Integrative Health to discuss treatment plans tailored to your unique needs.

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FAQs About Gut Health

How Do I Know If My Gut Is Unhealthy?

Signs of an unhealthy gut often include persistent digestive symptoms such as bloating, gas, diarrhea, constipation, or abdominal pain. Many people also experience symptoms beyond digestive issues, including fatigue, mood changes, skin irritation, frequent infections, and food intolerances. Patterns that persist or worsen over time are often more meaningful than isolated symptoms.

How Do You Cleanse an Unhealthy Gut?

There is no single cleanse that reliably “fixes” gut health. Improving an unhealthy gut typically involves gradual, supportive changes—such as adjusting diet, reducing processed foods, managing stress, and supporting digestion—rather than extreme or short-term cleanses. For individuals with chronic symptoms, a personalized medical approach is often more appropriate than a generalized cleanse.

What Is a 7-day Gut Reset?

A 7-day gut reset is a short-term dietary or lifestyle plan intended to reduce inflammation and support digestion. While these programs may help some people feel better temporarily, they are not a comprehensive solution for underlying gut issues. Lasting improvements typically require longer-term, individualized strategies.

What Is Dysbiosis?

Dysbiosis is a term used to describe an imbalance in the gut microbiome, in which harmful or less beneficial microbes outweigh beneficial ones. This imbalance can affect digestion, immune function, inflammation, and gut–brain signaling, and may contribute to a wide range of symptoms throughout the body.

How Do Healthcare Providers Test for Gut Dysbiosis?

Healthcare providers may evaluate gut dysbiosis using a combination of clinical history, symptom patterns, and specialized testing. This can include stool testing to assess microbial balance, markers of inflammation, and digestive function, along with other laboratory tests depending on a person’s symptoms and medical history.

Can Poor Gut Health Affect Your Mood?

Yes, the gut and brain are closely connected, and poor gut health can influence mood, stress response, and cognitive clarity. Changes in gut bacteria and inflammation can affect neurotransmitters involved in emotional regulation, which is why anxiety, low mood, or brain fog sometimes accompany digestive issues.

Can Bad Gut Health Cause Skin Issues?

Gut health can play a role in skin conditions such as acne, rashes, eczema, or psoriasis. Imbalances in the gut may contribute to inflammation and immune responses that affect the skin, particularly when skin symptoms are persistent or resistant to topical treatments.