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The Blakely Lab at Florida Atlantic University

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c-fos labelling showing neuronal activation on a whole mouse brain. After immunolabelling and tissue clearing, brain was scanned on the Blaze Light Sheet Ultramicroscope. Credits: Lorena Areal, Paula Kurdziel and Jana Strickler.

Research in the Blakely laboratory is focused on how presynaptic plasma membrane transporter proteins support chemical signaling in the nervous system, how they mediate the entry of transmitter-like neurotoxins into neurons, and whether altered signaling in disease states is supported by genetic variations in transporter structure. Over the past decade, we have been actively involved in the molecular cloning of transporter genes, including the identification of transporters for norepinephrine, epinephrine, serotonin, dopamine, proline, creatine, and choline. Using modern techniques in molecular biology, biochemistry, imaging, and genetics, we apply a multi-disciplinary approach to understand how transporters are organized in the plasma membrane, how they recognize their substrates, how they are regulated, and whether defects in their activity, trafficking, or regulation contribute to altered behavior and physiology.



  Lab and Institute News

Congrats to Lorena Areal, Ph.D, postdoctoral fellow, for winning the third annual Art of Science contest.

Congratulations to Angelica Wiggins for successfully defending her undergraduate thesis in the FAU-Max Planck Honors Program. Read More

Congratulations to Dr. Osama Refai for his promotion to Research Assistant Professor of Biomedical Science in the FAU College of Science. Way to go Osama! Read More

FAU Stiles-Nicholson Brain Institute
June 8, 2021

A near-$10 million to Florida Atlantic University from David J. S. Nicholson will welcome an era of unprecedented research, education and discovery at FAU's John D. MacArthur Campus in Jupiter.

FAU Stiles-Nicholson Brain Institute
December 17, 2021

FAU Stiles-Nicholson Brain Institute announced today it has received $1 million from the Palm Health Foundation to launch and support its new Program in Computational Brain Science and Health (PCBSH).

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Laboratory Manager

The FAU Brain Institute is looking to hire a Laboratory Manager for the Randy Blakely lab.

Learn more

Randy Blakely
Randy D. Blakely, Ph.D.
Executive Director, FAU Stiles-Nicholson Brain Institute
Professor, Biomedical Science

Updated 5/9/2022