2023 Publications

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Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells.
Haque TT, Taruselli MT, Kee SA, Dailey JM, Pondicherry N, Gajewski-Kurdziel PA, Zellner MP, Stephenson DJ, MacKnight HP, Straus DB, Kankaria R, Jackson KG, Chumanevich AP, Fukuoka Y, Schwartz LB, Blakely RD, Oskeritzian CA, Chalfant CE, Martin RK, Ryan JJ.
Sci Signal. 2023 Sep 12;16(802):eabc9089. doi: 10.1126/scisignal.abc9089. Epub 2023 Sep 12.
PMID: 37699080

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Disruptive mutations in the serotonin transporter associate serotonin dysfunction with treatment-resistant affective disorder.
Støier JF, Jørgensen TN, Sparsø T, Rasmussen HB, Kumar V, Newman AH, Blakely RD, Werge T, Gether U, Herborg F.
medRxiv. 2023 Aug 29:2023.08.29.23294386. doi: 10.1101/2023.08.29.23294386. Preprint.
PMID: 37693601 Free PMC article.

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Divergent Actions of Renal Tubular and Endothelial Type 1 IL-1 Receptor Signaling in Toxin-Induced AKI.
Ren J, Liu K, Wu B, Lu X, Sun L, Privratsky JR, Xing C, Robson MJ, Mao H, Blakely RD, Abe K, Souma T, Crowley SD.
J Am Soc Nephrol. 2023 Aug 7. doi: 10.1681/ASN.0000000000000191. Online ahead of print.
PMID: 37545036

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Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences.
Mayer FP, Stewart A, Varman DR, Moritz AE, Foster JD, Owens AW, Areal LB, Gowrishankar R, Velez M, Wickham K, Phelps H, Katamish R, Rabil M, Jayanthi LD, Vaughan RA, Daws LC, Blakely RD, Ramamoorthy S.
bioRxiv. 2023 May 3:2023.05.03.539310. doi: 10.1101/2023.05.03.539310. Preprint.
PMID: 37205452

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Serotonin in the orbitofrontal cortex enhances cognitive flexibility.
Hyun JH, Hannan P, Iwamoto H, Blakely RD, Kwon HB.
bioRxiv. 2023 Mar 9:2023.03.09.531880. doi: 10.1101/2023.03.09.531880. Preprint.
PMID: 36945634

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Serotonin-releasing agents with reduced off-target effects.
Mayer FP, Niello M, Cintulova D, Sideromenos S, Maier J, Li Y, Bulling S, Kudlacek O, Schicker K, Iwamoto H, Deng F, Wan J, Holy M, Katamish R, Sandtner W, Li Y, Pollak DD, Blakely RD, Mihovilovic MD, Baumann MH, Sitte HH.
Mol Psychiatry. 2023 Feb;28(2):722-732. doi: 10.1038/s41380-022-01843-w. Epub 2022 Nov 9.
PMID: 36352123

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