Matthew S. Schrier, Ph.D.

Mentor: Ning Quan, Ph.D.

Affiliation: Florida Atlantic Stiles-Nicholson Brain Institute

Schrier is interested in how serotonin uptake is modified by inflammation in models of depression and fatigue. Increasing extracellular serotonin levels in the brain is believed to initiate the effects of many antidepressants. Schrier’s research seeks to elucidate the contribution of various brain cell types (particularly glial cells) in regulating extracellular serotonin in response to pro-inflammatory mediators, such as the cytokine interleukin-1. He also aims to understand the mechanisms by which this may occur.