Khalid A. Hanafy, M.D., Ph.D.

Headshot of Khalid A. Hanafy, M.D., Ph.D.

Research Associate Professor

777 Glades Road Building

Boca Raton, FL 33431

BC 71, Room 221

p: 561-955-2785

khanafy@health.fau.edu

Department: Biomedical Science


 

Biography

I am a neurointensivist (a neurologist with critical care training) fascinated by neuroinflammation after stroke, both ischemic and hemorrhagic. Our lab focuses on the role of the tissue resident macrophage, or microglia, in the brain. These sentinel cells serve the dual role of surveying the brain environment and recruiting other leukocytes, or quiescing an inappropriate inflammatory response. Our work has demonstrated that the microglial Toll-like Receptor 4 (TLR4) receptor is involved in increasing inflammation after hemorrhagic stroke, while the microglial Heme-Oxygenase 1 (HO-1) enzyme is involved in decreasing this inflammation.

Currently, we are working on a way to modulate the inflammatory pathways after hemorrhagic stroke to decrease inflammation, and test these novel therapeutics in brain organoids.

Education

  • 1996, BS (Honors) Bioengineering, UC Berkeley
  • 1997, BS Chemical Engineering, UC Berkeley
  • 2004, MD, University of Texas at Houston Health Science Center/MD Anderson Cancer Center Medical Scientist Training Program (MSTP)
  • 2004, PhD in Molecular Biology, with Dr. Ferid Murad (1998 Nobel Laureate), University of Texas at Houston Health Science Center/MD Anderson Cancer Center MSTP

Postdoctoral Training

  • 6/2005: Intern, Medicine, University of Texas at Southwestern/Parkland Hospital
  • 6/2008: Resident, Neurology, University of Texas at Houston Health Science Center/MD Anderson Cancer Center
  • 6/2010: Fellow, Neurological Critical Care, Columbia University

Work History

  • 8/2010-3/2014: Instructor, Neurology, Harvard Medical School
  • 3/2014-6/2020: Assistant Professor, Neurology, Harvard Medical School
  • 7/2020-6/2022: Associate Professor, Neurology, Florida Atlantic University
  • 6/2022-present: Professor, Neurology, Florida Atlantic University

Peer-Reviewed Publications

Additional Information
The Charles E. Schmidt College of Medicine offers students a variety of educational programs and degrees.
Address
Charles E. Schmidt College of Medicine
Florida Atlantic University
777 Glades Road, BC-71
Boca Raton, FL 33431
(561) 297-4828