Slide 4 of 24
Notes:
Absorption depends on the route of administration
Drug distribution depends on how soluble the drug molecule is in fat (to pass through membranes) and on the extent to which the drug binds to blood proteins (albumin)
Drug elimination is accomplished by excretion into urine and/or by inactivation by enzymes in the liver (metabolism)
Excretion by the kidneys, liver, blood & brain
