Connecting Wildlife, Environmental and Public Health
The primary focus of Harbor Branch population health and epidemiology research is the interplay of marine mammal, human, and environmental health, as embodied in the One Health concept. The resulting research on marine mammal health, infectious disease and environmental epidemiology has illustrated the dolphin’s role as a sentinel organism for human and ecosystem health. Bolstered with staff expertise in study design, statistical analysis and data management in both wildlife and human research, the program recently produced one of the pioneering studies connecting animal and human health, which demonstrated elevated mercury concentrations in dolphins and humans who consume fish from Florida’s Indian River Lagoon.
This research is funded in part by proceeds from Florida's Protect Wild Dolphins specialty license plate.
Dolphin Health and Environmental Risk Assessment (HERA)
This work began in 2002 with the dolphin Health and Environmental Risk Assessment Project under the guidance of Dr. Greg Bossart and Dr. John Reif. Data from the HERA project , provided the foundation for epidemiology research at Harbor Branch. Epidemiology continues to play a significant role in the execution and analysis of this multidisciplinary project including analysis of the all HERA data, study design, and analysis and integration of multiple streams of research data. This effort is supported by sales of Protect Wild Dolphins Florida specialty license plates.
This work involves surveillance and retrospective analysis of data on the prevalence and patterns of antibiotic-resistant organisms in Indian River Lagoon bottlenose dolphins combined with environmental data to assess correlations with natural and anthropogenic stressors using both classical microbiology and emerging molecular methodology. It is supported by sales of Protect Wild Dolphins Florida specialty license plates.
Mercury and Emerging Contaminants
Ongoing research on mercury concentrations in bottlenose dolphins has led to multiple research questions including the physiologic effects of chronic exposure, the movement of mercury in the food web and associated risks for local human populations. The data and analysis will aid understanding of disease susceptibility and virulence of infectious and chronic disease. This work is supported by sales of Protect Wild Dolphins Florida specialty license plates (free-ranging dolphin sampling and physiological effects), the Brockman Trust (toxogenomics and human exposure) and Georgia Aquarium (dolphin and prey species).
Multiple epidemiological studies have established the prevalence of infectious disease with zoonotic potential. The presence of these diseases in dolphins and in the environment represents a potential risk to coastal human populations. In order to understand the potential public health relevance, multiple epidemiological studies are ongoing. Continued surveillance in conjunction with environmental and human disease monitoring will provide valuable insight. This work is supported by sales of Protect Wild Dolphins Florida specialty license plates.
Lobomycosis is a chronic fungal disease of the skin that has been document in humans and dolphins, but the causative agent, Lacazia loboi, has never been cultured. The lack of in vitro culture results in diagnosis delays and the inability to determine an effective treatment or to identify environmental reservoirs for disease. Harbor Branch research has demonstrated a high prevalence of the disease in the southern Indian River Lagoon dolphin population, which, along with the potential for human health impact, drives epidemiology research. Culture attempts and molecular characterization have the potential to improve the understanding of this unique pathogen and its presence in the environment. This effort is supported by sales of Protect Wild Dolphins Florida specialty license plates.
Pathophysiology of Stress
Pathophysiology of Stress in Wild and Managed-Care Bottlenose Dolphins (Tursiops truncatus) is a study to characterize the pathophysiology of stress in wild and managed-care bottlenose dolphins and to establish relationships between markers of the stress response in cetaceans and immune function, dependent hormonal endpoints, hematology and serum chemistry parameters, biomarkers of stress, inflammation and metabolism and health status. The characterization of stress will aid in the understanding of disease susceptibility among dolphin populations, which is an essential step in understand the overall dynamics of health in and along the coastal region. This study is supported by the Office of Naval Research.
Adam Schaefer, M.P.H.